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doi: 10.1016/j.jconrel.2022.05.042

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In the following sections, the various direct mechanisms of acrolein toxicity such as protein and DNA adduction, and indirect mechanisms including induction of oxidative, mitochondrial, and ER stress, are critically discussed with possible connection to affected organs and pathological conditions

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It was hypothesized that these structural changes might be associated with the impairment of the endogenous scavenging pathways

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