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Interestingly, it was recently shown that transactivation of RON by c-MET may be a feature of cancer cells that are addicted to c-MET signaling [Benvenuti et al

Madison: American Society of Agronomy, Inc

By masking the thiol, the protein will be altered in its capacity to form disulfide bonds and to fold into different functional (perhaps active) conformations

Kelpke, S
