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Yuan H, Li X, Zhang X, Kang R, Tang D

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Ahmed AY, Aowda SA, Hadwan MH

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Treatment of HCC cells with ADI-PEG20 downregulates the key enzymes of pyrimidine synthesis in the TCA cycle, carbamoyl phosphate synthetase 2, thymine synthase (TS), aspartate transcarbamylase and dihydrooratase (CAD) and malate dehydrogenase 1 (MDH-1) activities, making tumor cells more susceptible to 5-fluorouracil (5-FU)

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GLUTEN-FREE, SODIUM-FREE, AND KOSHER CERTIFIED, EACH CAPSULE CONTAINS 100 MG

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