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doi: 10.1159/000436956
In contrast, WT flies suppress completely the direct effect of these drugs in the same chronic treatment condition and show no change in final mitochondrial H 2 O 2 concentration (Fig
Notably, the DHODH inhibitor brequinar was shown to suppress tumor growth in vivo, an effect partially attributed to enhanced ferroptotic vulnerability in GPX4-low tumors
Phase 2 and pharmacodynamic study of oral forodesine in patients with advanced, fludarabine-treated chronic lymphocytic leukemia
