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Similarly, vitamin B12 (cobalamin) subclinical deficiency is present in an estimated 2% to 26% of the population, varying based on the definition and the measuring method applied [220,227]
Collectively, the above findings indicate that EUP exerts therapeutic effects on OP in murine models by restoring cortical bone thickness, increasing mineralized bone area, elevating OBs numbers, and reducing OCs presence along the cortical bone surface

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