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Int J Dev Neurosci 80:287302

Moreover, the inhibition of autophagy can exacerbate the progress of some inflammatory and autoimmune diseases through the production of inflammatory cytokines 40

Bax, when released from Bcl-2, will induce a mitochondrial permeability transition (MPT) in response to this oxidative stress [238], which will trigger cytochrome c to be released from mitochondria, activating caspase-mediated apoptosis [235]
