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The mechanism of ADE of disease associated with dengue therefore depends on three factors: the circulation of multiple strains of a virus that have variable antigenicity, a virus that is capable of replication in FcR-expressing myeloid cells and sequential infection of the same person with these different viral serotypes

Do not self-administer without professional direction

Repeated injections then begin weakening the tissue structurally over time, increasing the risk of plantar fascia rupture
