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While high B12 levels can indicate underlying health issues, they may also occur due to over-supplementation or vitamin injections, which dont always signify a medical problem 5

Vitamin B12 is absorbed in our body with the help of a protein produced in your stomach called the intrinsic factor

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194,195 The activated PI3K catalyzes the conversion of membrane phospholipid Phosphatidylinositol-4,5-bisphosphate (PIP2) into Phosphatidylinositol-3,4,5-trisphosphate (PIP3)