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Upon contact and recognition, immature dendritic cells are activated, altering their morphology to activate both CD4 and CD8 T cells for a robust adaptive immune response (Liu and Cao, 2015)
From the immunological perspective, the ideal graft sites should have restricted immune responses and ensure the lowest rate of islet loss
doi: 10.1074/jbc.275.6.4507
[PUBMED Abstract] Jeha S, Goto H, Baruchel A, et al.: Patient-Level Meta-analysis of Clofarabine in Acute Lymphoblastic Leukemia
