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In rodent and primate metabolic models, amylin analogue administration has been shown to attenuate glucagon-driven hepatic glucose output and reduce postprandial glycemic excursions, independently of insulin secretion (Verchere et al., Proceedings of the National Academy of Sciences, 1996

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Rather than injecting large doses infrequently (most of which you will flush out within an hour), its much better to inject smaller, daily doses

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We observed fewer spines on mutant cells compared with controls (Fig

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Madl T, et al

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