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The brain-safe effects saw in IGF1 LR3 research appear to involve similar signaling pathways but with outcomes specific to neural tissue

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This study showed that plasma exposure times longer than 2 min resulted in hemorheological alterations such as hemolytic activity, elongation index and higher aggregation index than in the untreated RBC samples

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Afterwards, AA-PE and AdA-PE catalyzed by LPCAT3 are oxidized by ALOX15 to generate LPO, leading to ferroptosis [46]

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