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We also shed light on results of studies evaluating the effects of targeting one or more of these factors on overcoming resistance to anti-VEGF therapies
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2.3.3 Assessment of the oxidative stress markers and mtNOS activity in heart mitochondria Biochemical indicators of oxidative stress such as the rate of formation of superoxide (O 2 ) and hydrogen peroxide pools (H 2 O 2 ) were measured in the suspension of heart mitochondria
