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[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Celestino-Soper PB, Violante S, Crawford EL, Luo R, Lionel AC, Delaby E, Cai G, Sadikovic B, Lee K, Lo C, Gao K, Person RE, Moss TJ, German JR, Huang N, Shinawi M, Treadwell-Deering D, Szatmari P, Roberts W, Fernandez B, Schroer RJ, Stevenson RE, Buxbaum JD, Betancur C, Scherer SW, Sanders SJ, Geschwind DH, Sutcliffe JS, Hurles ME, Wanders RJ, Shaw CA, Leal SM, Cook EH, Jr, Goin-Kochel RP, Vaz FM, Beaudet AL

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Previous quantitative analysis of urine collected from rats treated with furan at doses of 0.1, 0.5 and 2 mg/kg bw for 5 and 28 days demonstrated a linear correlation between external dose and urinary excretion of NAcLys-BDA and cyclic GSH-BDA, but also revealed substantial background levels of NAcLys-BDA in urine of untreated animals (Karlstetter and Mally 2020)

Formation of creatine, though is also dependent upon methylation, and so the use of ATP technically involves methylation