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PubMed, Zappacosta, Bruno, et al

The three-level hierarchical model showed no significant difference among all comparisons of administration routes
The following timeframes are supported by clinical trial data and prescribing information: Nausea: Most commonly peaks in the first one to two weeks at each dose level, then improves significantly over weeks three to four

10.1038/s41586-019-1034-5 117 KerkeniM.TrabelsiK.KerkeniM.BoukhrisO.AmmarA.SalemA.et al (2024)
