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To promote their growth, tumor cells require significant nutrition to generate metabolites that contribute to modifying the tumor microenvironment (TME) [5, 6]

300 FUS is also capable of temporarily disrupting the blood-brain barrier, allowing therapeutics to enter the brain and undesired materials to depart from the brain

Yu and Liu, 2020)

Overall, moderate-dose and long-term LA administration in humans is rarely associated with serious side effects
