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11 In this review, we outline the mechanisms and targets of such, and discuss some of the major drug trials in NASH

Inhibition of key digestive enzymes such as -amylase and -glucosidase, by polyphenols involved in the digestion and absorption of carbohydrates, is one of the principal mechanisms, thereby mitigating postprandial hyperglycemia (Amoako & Awika, 2016)

However, an association between HCN4 (hyperpolarization-activated cyclic nucleotide channel 4) rare variants and MVP have been reported