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chronic or excessive activation may disrupt metabolic homeostasis or trigger off-target effects

As exhibited in a prior study, increased MAM formation elevated cytoplasmic Ca 2+ levels, which promoted the phosphorylation of serum response factor (SRF) and its binding to the vascular endothelial growth factor receptor 2 (VEGFR2) promoter, producing VEGFR2 and thereby promoting inflammatory angiogenesis
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Erscheint die Lsung trb, verfrbt oder enthlt sie sichtbare Schwebstoffe, sollte das Flschchen verworfen werden

10.1073/pnas.86.23.9480 [DOI] [PMC free article] [PubMed] [Google Scholar] 96.Vanderslice P, Ballinger SM, Tam EK, Goldstein SM, Craik CS, Caughey GH
