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Among all the HSB tissues examined, liver and proximal intestine were most sensitive to dietary glycine supplementation with regard to GSH synthesis, as was skeletal muscle regarding creatine synthesis
However, doses above 2.4 mg showed diminishing returns due to increased gastrointestinal side effects, including nausea, vomiting, and diarrhea
10.1007/s00441-016-2464-0 124
