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However, long-term hyperglycemia-related conditions cause mTOR inhibition leading to autophagy dysregulation, hence the reason for the neuronal cell death in DR

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For one, the role of the NMDAR can vary depending on activity level

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10.1016/j.neuron.2020.08.012 Neuron 170 LipovE.GluncicV.LukiI

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