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Glutathione is a powerful antioxidant that has been linked to many chronic conditions such as cancer, cardiovascular disease, liver, and neurodegenerative diseases
In addition, astrocyte mitochondrial dysfunction triggers a pro-inflammatory response, whereas normal mitochondria inhibit microglia activation and the release of pro-inflammatory factors, such as TNF- and IL-6, indirectly protecting neurons from inflammation-related apoptosis [54]
