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Peptides for depression enhance neuroplasticity by upregulating BDNF/TrkB signaling, helping the brain form new connections that restore emotional resilience

Following 3 h of drug treatments, 5 M of the cell-permeable, ROS-sensitive dye CellROX Deep Red (Invitrogen, Stockholm, Sweden) was added to each sample and incubated at 37 C for 30 min

Histone modification analyses have documented GHK-Cu-associated changes in acetylation and methylation marks on histones H3 and H4, particularly at gene loci demonstrating altered transcriptional activity

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