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10.1523/JNEUROSCI.4129-11.2012 92 KazamaM.KatoY.KakitaA.NoguchiN.UranoY.MasuiK.et al

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Patrolling The enemy wanders back and forth on a set route

Evidence suggests multiple interrelated pathways of liver injury: Nicotine-induced injury : Nicotine is metabolized in the liver via CYP2A6, where it activates 7-nicotinic acetylcholine receptors (7-nAChR), leading to oxidative stress, mitochondrial dysfunction, and pro-fibrotic signaling [36, 125, 126]
