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62 Thus, consistent with the very low levels of LPO, 55,62 lysosomal ferrous iron translocated into mitochondria promotes MPTP opening and APAP-induced cell death through facilitation of protein nitration, rather than generation of LPO under normal conditions
Clin Exp Metastasis 21 : 755764 Savage SA et al
Human Reproductive Biology (Academic Press, 2013)
The 200,000+ annual pregnancies involving acetaminophen use in women with compromised glutathione suggests it may be one environmental factor that interacts with underlying vulnerabilities
