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% of iron saturation is increased
Consequently, inhibition of its small subunit xCT (SLC7A11) by the small molecule erastin results in cystine depletion and ferroptosis 29

The activity of LDHA and the glycolytic end product L-lactate level were significantly reduced in T98G cells along with GSTM3 gene suppression, which implied that GSTM3 downregulation might prevent cell invasion

Additional findings indicate potential benefits in experimental gastrointestinal injury models, including attenuation of inflammatory responses and enhanced mucosal resilience (2)
