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In one large study, 39% of patients with deficiency had neurologic manifestations, and in almost 80% of these cases, the neurologic symptoms were the sole or dominant manifestation of the deficiency (96)

A Cochrane review supports the use of high-dose vitamin B 12 (1 mg and 2 mg daily) in elevating serum vitamin B 12 level and achieving haematological and neurological responses, even in patients with PA or with ileal resection.58 The recommendation for oral replacement is 1 mg daily for a month, and then 125 to 250 g daily as maintenance dose for patients with dietary insufficiency and food-cobalamin malabsorption, while for PA the maintenance dose is 1 mg daily.29 Vitamin B 12 does not have side-effects even when prescribed in large doses.59 However, hypokalaemia, resulting from uptake of circulating potassium by newly growing and dividing haematopoietic cells, can be severe or sometimes life-threatening

Vitamin B12 additionally supports muscular physiology, the treatment of infertility, and tetany and paresis as an adjunct to calcium and magnesium therapy

In particular, the dark meat parts of the birds, such as the legs, thighs, and wings
