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FIGURE 1 2 Trimethylamine N-oxide and chronic kidney disease 2.1 Trimethylamine N-oxide is a risk factor for chronic kidney disease Risk factors for chronic kidney disease are various, including disease factors (Diabetes, hypertension, autoimmune diseases, systemic infections, urinary tract infections, acute kidney injury, etc.), Sociodemographic factors (age, gender, ethnicity, and family history of CKD, etc.), and lifestyle factor (smoking, heavy alcohol use, obesity, etc.) (Taal and Brenner, 2008

doi: 10.2165/00126839-200203040-00001

Montoya M, Morrison JA, Arrignon F, et al

The effects of O 2 are magnified because they lead to the formation of other free radicals and oxidizing agents (Pietta 2000)