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These medications have been shown to reduce relapse to opioid use, overdose, and HIV and HCV transmission, as well as improve other health outcomes.47 Buprenorphine is a partial -opioid agonist used for the maintenance treatment of opioid use disorder.2 Buprenorphine has potential merits, including a lower overdose risk and low ceiling effect for respiratory depression, fewer pharmaceutical interactions, and less risk of QTc-prolongation when compared to methadone.8 Buprenorphine is available in three formulations: sublingual films and tabs and buprenorphine extended-release injection (Sublocade ).4,6,7,9 The extended-release injectable formulation was approved by FDA in November 2017

Sterile water without preservatives reduces shelf life compared to bacteriostatic water

You can incorporate wine, cognac or whiskey, hot sauce or Worcestershire sauce, fish sauce or soy sauce

Bacteria, dust, and skin oils can all degrade sensitive peptide chains