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They were found to inhibit CYP-2D6 markedly, CYP-2C9 moderately, and CYP-2C19 and CYP-3A4 mildly to moderately
Moreover, DAQs can be detoxified through reactions with NAC or L -cysteine to form DAQ conjugation adducts [151, 152]
doi: 10.1016/j.cell.2007.11.028

[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Knezevic M., Gojkovic S., Krezic I., Zizek H., Vranes H., Malekinusic D., Vrdoljak B., Knezevic T., Horvat Pavlov K., Drmic D., et al