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5-amino-1mq nnmt inhibition mechanism Nicotinamide N-Methyltransferase in Cardiovascular Diseases: Metabolic Regulator and Emerging Therapeutic Target 5-Amino-1MQ 5mg | 10-Vial Kit
Description
doi: 10.1021/acs.jmedchem.7b00389

A one-way analysis of variance (ANOVA) with Dunnetts posthoc test was used to compare multiple groups (different inhibitor treatments or concentration effects in cellular assessments) to controls

Importantly, methylquinolinium analogues displayed high selectivity, not inhibiting related SAM-dependent methyltransferases or enzymes in the NAD + salvage pathway

5-Amino-1MQ: No established human safety profile exists
