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[DOI] [PMC free article] [PubMed] [Google Scholar] Haberzettl P., Vladykovskaya E., Srivastava S., Bhatnagar A
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B12 deficiency disrupts the methylation cycle, reducing the availability of the methyl groups needed to activate key enzymes in melanin synthesis
Moreover, the carbon skeleton of glutamine helps sustain mitochondrial function by feeding into alternative TCA cycle routes, thereby supporting mitochondrial bioenergetics despite the downregulation of canonical OXPHOS (96)
