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The conversion of the amino acid tryptophan to vitamin B3 also requires riboflavin and supports why B vitamin supplementation should be balanced

Such multigene signatures offer greater robustness and predictive power than single-gene markers

Additionally, the levels of anti-inflammatory cytokines are often elevated in patients with major depressive disorder (130, 131), further highlighting the key role of inflammation in depression

Unlike glutathione, B12 cannot be produced by the body, meaning it must be obtained through diet or supplementation
