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Description
H 2 O 2 -dependent signaling occurs with a lower intracellular concentration of approximately 1-100 nM, mediating reversible oxidation of the thiolate group to a sulfenic group (Cys-SOH) and covalent linkage of cysteine residues by disulfide bonds (Cys-S-S-Cys) altering its activity and localization (7)
109 Thus, a ferroptosis inhibitor alone cannot be used to support the conclusion of ferroptosis
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