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Description
Acute brain damagetrauma and ischemia Acute trauma, ischemia and stroke are characterized by prominent increases in the presence and activity of Cx43 hemichannels in astrocytes, contributing to the secondary damage of the nervous tissue 478

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Multiple mechanisms, including oxidative stress, inflammation, apoptosis, and reduction of neurotrophic factor, have been proposed to induce neurocognitive deficits due to IH (Figure 2)
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