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Description
In winter, your skin barrier tends to weaken faster, cell turnover slows down, and pigmentation often becomes more visible

Angus, K., Asgharifar, S

[DOI] [PubMed] [Google Scholar] 110.Roes E.M., Raijmakers M.T., De Boo T.M., Zusterzeel P.L., Merkus H.M., Peters W.H., Steegers E.A

The earliest studies of MOR phosphorylation established that the receptor is phosphorylated more efficiently following activation by high-efficacy agonists, such as DAMGO or etorphine, than by low-efficacy agonists such as morphine in cell lines (Yu et al., 1997
