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Here, we consider why the TGF signalling pathway is a drug target, the potential clinical applications of TGF inhibition, the issues arising with anti-TGF therapy and how these might be tackled using personalized approaches to dosing, monitoring of biomarkers as well as brief and/or localized drug-dosing regimens

The significant features were selected by recursive feature elimination (RFE) methods of the training dataset

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

Headache 38 , 3942 (1998)
