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[2] Heffernan, M., Summers, R
Laskin, D

These findings remain in early exploratory stages and warrant further rigorous study

Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation