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In addition to excitotoxicity, Aos can inflict injury to brain cells through oxidative stress
For the activated state, CBS FL-CHis was diluted to 0.75 mg/ml (11.25 M) into 25 mM HEPES, pH 7.5, 200 mM NaCl, 2.0 mM TCEP, 0.005% (v/v) tween-20, 5 mM SAM
Ferritinophagy is defined as the selective autophagic degradation of ferritin, which prompts the accumulation of cytosolic Fe 2+

In controlled experiments, this combination of effects leads to quicker healing