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Recently, researchers characterized a translocation involving histone demethylase KDM5A that resulted in fusion of the H3K4me3-binding PHD finger of KDM5A to the transcriptional activator NUP98, a common leukemia translocation partner, in an acute myeloid leukemia patient (Islam et al
Autophagosomes appear to predominantly breakdown cell matrix components with no apparent commensurate degradation of organelles [28]
November 2025
However despite the increase in egtA expression, intracellular EGT levels did not increase upon addition of H 2 O 2 , most likely due to reactivity with ROS species as we observed for purified EGT
