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The bacteria use a convoluted metabolic route to produce vitamin B 12 (Calvillo et al., 2023)
Furthermore, the results are not always predictable as HA gels are extremely hydrophilic, meaning they can absorb a lot of water
Formulation and delivery innovations can expand access through polyethylene glycol-sparing lipids, lyophilization and mucosal or dermal routes that support repeat dosing and stability
