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How Neurotransmitter Imbalances Affect Mood and Cognition Imbalances in neurotransmitters can disrupt your mood and cognition

38 subjects were not matched (11 not treated, 14 treated with ALCAR 3 g/day and 13 treated with ALCAR 1.5 g/day and were excluded from the analyses (Fig

10.3390/molecules28155904 98 RongS.ZhaoY.BaoW.XiaoX.WangD.NusslerA

The deficiency of free CoA limits the efficiency of the Krebs cycle in activating anaerobic glucose metabolism (which inhibits pyruvate dehydrogenase activity, which is responsible for the conversion of pyruvate to acetyl-CoA in aerobic glucose metabolism in cells of the human organism), causing an increase in the concentration of toxic lactate in tissues [58,78,79]