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Immunity takes a key role in neural development of both central and peripheral nervous system, regulating several aspects such as neuronal proliferation, synapse formation, and plasticity, together with the removal of apoptotic neurons

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One of the critical factors underlying these complications is oxidative stress, which is primarily driven by free radicals such as ROS and RNS

Brown adipose tissue (BAT) is integral to lipid metabolism as it increased heat production through enhanced energy metabolism (Jung et al., 2019)