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Since LCFAs preferentially undergo FAO in mitochondria, alterations in LCA levels may reflect changes in mitochondrial FAO in E4s with age compared to E2 and E3 mice

doi: 10.33263/BRIAC111.79817993 150 ChenLLiJLuoCLiuHXuWChenGet al

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That spells trouble for mitochondria, which become starved of energy and filled with cellular waste
