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Shaking causes foaming and can denature the peptide through mechanical stress

1 Introduction Tumor-associated macrophages (TAMs), a dominant immune cell population in the tumor microenvironment (TME), significantly influence cancer progression ( Ferroptosis represents a metabolically driven form of regulated cell death that is fundamentally distinct from apoptosis, necroptosis, and pyroptosis ( Figure 1

It also damages mitochondria, produces more ROS, and contributes to disease progression

doi: 10.1021/tx990161k
