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Key Takeaways GHK-Cu is a copper binding tripeptide, not a hormone It modulates extracellular matrix remodeling Its effects are local rather than endocrine Human evidence supports skin and wound applications Systemic anti aging claims exceed available data Sources Pickart L, Thaler MM

(2017) reported that SA and IAA influence OsGPX expression under salt and cold stress, suggesting hormone-mediated modulation of antioxidant responses

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