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Description
The symptoms can be subtle initially and may overlap with manifestations of liver disease itself, making recognition challenging
Other options that have been studied in patients with aggressive PRLomas include targeted oncological agents, such as everolimus (216, 217), bevacizumab (64, 218, 219), lapatinib (220, 221) and immune-checkpoint inhibitors (ipilimumab and nivolumab) (218, 219, 222, 223)
Apr 2008;8(4):605-615
Clinicians will typically try standard prenatal vitamins or oral supplementation first, resorting to IM/IV B-complex therapy if those are inadequate or not feasible
