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Description
RBCs are particularly susceptible to oxidative stress due to the lack of nuclei needed for protein synthesis, the absence of mitochondria capable of supplying NADPH outside of the PPP, and a high iron content that drives Fenton chemistry 8

Additionally, polymorphisms in other genes involved in SFN metabolism and response have been explored

has explored new GlyT1 inhibitor analogs, including pyrrolidine and 4,5-dihydropyrrazole derivatives (Korablina et al

10.1007/s10787-006-1531-7 116 SikiricP.SeiwerthS.BrcicL.SeverM.KlicekR.RadicB.et al (2010)
