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People with a lower starting body mass index tended to lose the highest percentage, while those carrying more weight lost a larger absolute number of pounds even if the percentage read lower
When cagrilintide is paired with semaglutide as CagriSema, the gap narrows23% for CagriSema versus 25.5% for Zepbound in a direct head-to-head trialbut Zepbound still holds a modest edge
This difference underscores how these studies are complementary parts of the combination product development cycle
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