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394,395 As mentioned above, HSF1 is subject to numerous PTMs that govern its activation or inhibition at different levels, and the mediators of these PTMs themselves, or their upstream receptors or sensors, help integrate multiple different stimuli in the HSF1-mediated response
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Therefore, synbiotics, i.e., a mixture of prebiotics and probiotics, may help control the diseased state
There is a small, but possible, chance of reaction
