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Individuals who express the ADH1B*2 allele are, therefore, much less likely (deemed protective) to abuse alcohol since they rapidly produce large quantities of acetaldehyde resulting in rapid onset of severe side effects such as tachycardia, nausea, flushing, and vomiting

The effectiveness of clomipramine hydrochloride capsules for the treatment of OCD was demonstrated in multicenter, placebo-controlled, parallel-group studies, including two 10-week studies in adults and one 8-week study in children and adolescents 10 to 17 years of age

PMID 28770615

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