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Fang XS, Wen XY, Zhou L, Jiang YJ, Wang LF

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3.1 The downregulation of Nrf2/system X c axis Defending against ferroptosis starts right at the cell surface

Initial liver biopsy revealed active fulminant hepatitis with extensive centrilobular necrosis, approximately 25% hepatocellular viability, and mixed inflammatory infiltrates consisting of lymphocytes, histiocytes, scattered eosinophils, and occasional neutrophils